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In Vitro Modeling of Bradykinin-Mediated Angioedema States

Kinins (peptides related to bradykinin, BK) are formed from circulating substrates, the kininogens, by the action of two proteases, the kallikreins. The only clinical application of a BK receptor ligand, the B(2) receptor antagonist icatibant, is the treatment of the rare hereditary angioedema (HAE)...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Marceau, François, Bachelard, Hélène, Charest-Morin, Xavier, Hébert, Jacques, Rivard, Georges E.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7559923/
https://ncbi.nlm.nih.gov/pubmed/32824891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13090201
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