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In Vitro Modeling of Bradykinin-Mediated Angioedema States
Kinins (peptides related to bradykinin, BK) are formed from circulating substrates, the kininogens, by the action of two proteases, the kallikreins. The only clinical application of a BK receptor ligand, the B(2) receptor antagonist icatibant, is the treatment of the rare hereditary angioedema (HAE)...
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| Pubblicato in: | Pharmaceuticals (Basel) |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7559923/ https://ncbi.nlm.nih.gov/pubmed/32824891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13090201 |
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