Comparing Pathways of Bradykinin Formation in Whole Blood From Healthy Volunteers and Patients With Hereditary Angioedema Due to C1 Inhibitor Deficiency

Multiple pathways have been proposed to generate bradykinin (BK)-related peptides from blood. We applied various forms of activation to fresh blood obtained from 10 healthy subjects or 10 patients with hereditary angioedema (HAE-1 or −2 only) to investigate kinin formation. An enzyme immunoassay for...

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Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Charest-Morin, Xavier, Hébert, Jacques, Rivard, Georges-Étienne, Bonnefoy, Arnaud, Wagner, Eric, Marceau, François
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2018
Sujets:
Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176197/
https://ncbi.nlm.nih.gov/pubmed/30333824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02183
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