Photoreceptor protection via blockade of BET epigenetic readers in a murine model of inherited retinal degeneration

BACKGROUND: The bromodomain and extraterminal domain (BET) family proteins (BET2, BET3, and BET4) “read” (bind) histone acetylation marks via two distinct bromodomains (Brom1 and Brom2) facilitating transcriptional activation. These epigenetic “readers” play crucial roles in pathogenic processes suc...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Neuroinflammation
Main Authors: Zhao, Lei, Li, Jun, Fu, Yingmei, Zhang, Mengxue, Wang, Bowen, Ouellette, Jonathan, Shahi, Pawan K., Pattnaik, Bikash R., Watters, Jyoti J., Wong, Wai T., Guo, Lian-Wang
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5248448/
https://ncbi.nlm.nih.gov/pubmed/28103888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0775-4
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker