BET Bromodomain Blockade Mitigates Intimal Hyperplasia in Rat Carotid Arteries

BACKGROUND: Intimal hyperplasia is a common cause of many vasculopathies. There has been a recent surge of interest in the bromo and extra-terminal (BET) epigenetic “readers” including BRD4 since the serendipitous discovery of JQ1(+), an inhibitor specific to the seemingly undruggable BET bromodomai...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Wang, Bowen, Zhang, Mengxue, Takayama, Toshio, Shi, Xudong, Roenneburg, Drew Alan, Craig Kent, K., Guo, Lian-Wang
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740308/
https://ncbi.nlm.nih.gov/pubmed/26870791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2015.09.045
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados