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A single active site residue directs oxygenation stereospecificity in lipoxygenases: Stereocontrol is linked to the position of oxygenation

Lipoxygenases are a class of dioxygenases that form hydroperoxy fatty acids with distinct positional and stereo configurations. Several amino acid residues influencing regiospecificity have been identified, whereas the basis of stereocontrol is not understood. We have now identified a single residue...

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Bibliografiske detaljer
Main Authors: Coffa, Gianguido, Brash, Alan R.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC524819/
https://ncbi.nlm.nih.gov/pubmed/15496467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406727101
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