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Stereocontrol of Arachidonic Acid Oxygenation by Vertebrate Lipoxygenases: NEWLY CLONED ZEBRAFISH LIPOXYGENASE 1 DOES NOT FOLLOW THE ALA-VERSUS-GLY CONCEPT
Animal lipoxygenases (LOXs) are classified according to their specificity of arachidonic acid oxygenation, and previous sequence alignments suggested that S-LOXs contain a conserved Ala at a critical position at the active site but R-LOXs carry a Gly instead. Here we cloned, expressed, and character...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3199522/ https://ncbi.nlm.nih.gov/pubmed/21880725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.259242 |
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