Stereocontrol of Arachidonic Acid Oxygenation by Vertebrate Lipoxygenases: NEWLY CLONED ZEBRAFISH LIPOXYGENASE 1 DOES NOT FOLLOW THE ALA-VERSUS-GLY CONCEPT

Animal lipoxygenases (LOXs) are classified according to their specificity of arachidonic acid oxygenation, and previous sequence alignments suggested that S-LOXs contain a conserved Ala at a critical position at the active site but R-LOXs carry a Gly instead. Here we cloned, expressed, and character...

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Bibliografiske detaljer
Main Authors: Jansen, Christian, Hofheinz, Katharina, Vogel, Robert, Roffeis, Jana, Anton, Monika, Reddanna, Pallu, Kuhn, Hartmut, Walther, Matthias
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Enzymology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199522/
https://ncbi.nlm.nih.gov/pubmed/21880725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.259242
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