An E2-guided E3 Screen Identifies the RNF17-UBE2U Pair as Regulator of the Radiosensitivity, Immunodeficiency, Dysmorphic Features, and Learning Difficulties (RIDDLE) Syndrome Protein RNF168

Protein ubiquitination has emerged as a pivotal regulatory reaction that promotes cellular responses to DNA damage. With a goal to delineate the DNA damage signal transduction cascade, we systematically analyzed the human E2 ubiquitin- and ubiquitin-like-conjugating enzymes for their ability to mobi...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Guo, Yingying, An, Liwei, Ng, Hoi-Man, Sy, Shirley M. H., Huen, Michael S. Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
DNA and Chromosomes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5247668/
https://ncbi.nlm.nih.gov/pubmed/27903633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.758854
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