Structural basis for role of ring finger protein RNF168 RING domain

Ubiquitin adducts surrounding DNA double-strand breaks (DSBs) have emerged as molecular platforms important for the assembly of DNA damage mediator and repair proteins. Central to these chromatin modifications lies the E2 UBC13, which has been implicated in a bipartite role in priming and amplifying...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Xiaoqin, Chen, Jie, Wu, Minhao, Wu, Huakai, Arokiaraj, Aloysius Wilfred, Wang, Chengliang, Zhang, Weichang, Tao, Yue, Huen, Michael S.Y., Zang, Jianye
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2013
Schlagworte:
Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575460/
https://ncbi.nlm.nih.gov/pubmed/23255131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.23104
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