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Put a RING on it: regulation and inhibition of RNF8 and RNF168 RING finger E3 ligases at DNA damage sites

RING (Really Interesting New Gene) domain-containing E3 ubiquitin ligases comprise a large family of enzymes that in combination with an E2 ubiquitin-conjugating enzyme, modify target proteins by attaching ubiquitin moieties. A number of RING E3s play an essential role in the cellular response to DN...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bartocci, Cristina, Denchi, Eros Lazzerini
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3705210/
https://ncbi.nlm.nih.gov/pubmed/23847653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00128
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