HLA–DRB1 Amino Acid Positions 11/13, 71, and 74 Are Associated With Inflammation Level, Disease Activity, and the Health Assessment Questionnaire Score in Patients With Inflammatory Polyarthritis

OBJECTIVE: Rheumatoid arthritis (RA) susceptibility HLA–DRB1 haplotypes based on amino acid positions 11/13, 71, and 74 predict radiographic damage. The mechanism of action is unknown, but it may be mediated by inflammation. We undertook this study to systematically investigate the effect of these a...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Ling, Stephanie F., Viatte, Sebastien, Lunt, Mark, Van Sijl, Alper M., Silva‐Fernandez, Lucia, Symmons, Deborah P. M., Young, Adam, Macgregor, Alexander J., Barton, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Rheumatoid Arthritis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5244675/
https://ncbi.nlm.nih.gov/pubmed/27274008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39780
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