The KAG motif of HLA-DRB1 (β71, β74, β86) predicts seroconversion and development of type 1 diabetes

BACKGROUND: HLA-DR4, a common antigen of HLA-DRB1, has multiple subtypes that are strongly associated with risk of type 1 diabetes (T1D); however, some are risk neutral or resistant. The pathobiological mechanism of HLA-DR4 subtypes remains to be elucidated. METHODS: We used a population-based case-...

詳細記述

保存先:
書誌詳細
出版年:EBioMedicine
主要な著者: Zhao, Lue Ping, Papadopoulos, George K, Lybrand, Terry P., Moustakas, Antonis K., Bondinas, George P., Carlsson, Annelie, Larsson, Helena Elding, Ludvigsson, Johnny, Marcus, Claude, Persson, Martina, Samuelsson, Ulf, Wang, Ruihan, Pyo, Chul-Woo, Nelson, Wyatt C., Geraghty, Daniel E., Rich, Stephen S., Lernmark, Åke
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2021
主題:
Research Paper
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8220560/
https://ncbi.nlm.nih.gov/pubmed/34153873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2021.103431
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