A new classification of HLA-DRB1 alleles based on acid–base properties of the amino acids located at positions 13, 70 and 71: impact on ACPA status or structural progression, and meta-analysis on 1235 patients with rheumatoid from two cohorts (ESPOIR and EAC cohort)

OBJECTIVE: To group HLA-DRB1 alleles based on acid–base properties of amino acids at positions 13, 70 and 71 and analyse their association with the presence of anticitrullinated peptide antibodies (ACPA) and structural progression in 2 cohorts of early rheumatoid arthritis (RA). METHODS: Patients wi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:RMD Open
Main Authors: Ruyssen-Witrand, Adeline, van Steenbergen, Hanna W, van Heemst, Jurgen, Gourraud, Pierre-Antoine, Nigon, Delphine, Lukas, Cédric, Miceli-Richard, Corinne, Jamard, Bénédicte, Cambon-Thomsen, Anne, Cantagrel, Alain, Dieudé, Philippe, van der Helm-van Mil, Annette H M, Constantin, Arnaud
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2015
Assuntos:
Rheumatoid Arthritis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654103/
https://ncbi.nlm.nih.gov/pubmed/26629363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/rmdopen-2015-000099
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados