Association Between Genetic Variation in FOXO3 and Reductions in Inflammation and Disease Activity in Inflammatory Polyarthritis

OBJECTIVE: Genetic variation in FOXO3 (tagged by rs12212067) has been associated with a milder course of rheumatoid arthritis (RA) and shown to limit monocyte‐driven inflammation through a transforming growth factor β1–dependent pathway. This genetic association, however, has not been consistently o...

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Vydáno v:Arthritis Rheumatol
Hlavní autoři: Viatte, Sebastien, Lee, James C., Fu, Bo, Espéli, Marion, Lunt, Mark, De Wolf, Jack N. E., Wheeler, Lily, Reynolds, John A., Castelino, Madhura, Symmons, Deborah P. M., Lyons, Paul A., Barton, Anne, Smith, Kenneth G. C.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
Rheumatoid Arthritis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5091631/
https://ncbi.nlm.nih.gov/pubmed/27214848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39760
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