Association Between Genetic Variation in FOXO3 and Reductions in Inflammation and Disease Activity in Inflammatory Polyarthritis

OBJECTIVE: Genetic variation in FOXO3 (tagged by rs12212067) has been associated with a milder course of rheumatoid arthritis (RA) and shown to limit monocyte‐driven inflammation through a transforming growth factor β1–dependent pathway. This genetic association, however, has not been consistently o...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Viatte, Sebastien, Lee, James C., Fu, Bo, Espéli, Marion, Lunt, Mark, De Wolf, Jack N. E., Wheeler, Lily, Reynolds, John A., Castelino, Madhura, Symmons, Deborah P. M., Lyons, Paul A., Barton, Anne, Smith, Kenneth G. C.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Rheumatoid Arthritis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5091631/
https://ncbi.nlm.nih.gov/pubmed/27214848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39760
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