Elevated collagen-I augments tumor progressive signals, intravasation and metastasis of prolactin-induced estrogen receptor alpha positive mammary tumor cells

BACKGROUND: The development and progression of estrogen receptor alpha positive (ERα+) breast cancer has been linked epidemiologically to prolactin. However, activation of the canonical mediator of prolactin, STAT5, is associated with more differentiated cancers and better prognoses. We have reporte...

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Bibliographic Details
Published in:Breast Cancer Res
Main Authors: Barcus, Craig E., O’Leary, Kathleen A., Brockman, Jennifer L., Rugowski, Debra E., Liu, Yuming, Garcia, Nancy, Yu, Menggang, Keely, Patricia J., Eliceiri, Kevin W., Schuler, Linda A.
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5244528/
https://ncbi.nlm.nih.gov/pubmed/28103936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-017-0801-1
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