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Prolactin cooperates with loss of p53 to promote claudin low mammary carcinomas
TP53 is one of the most commonly mutated genes in cancer. In breast cancer, it is mutated in about 40% of primary clinical tumors and is associated with poor survival. The mammotrophic hormone, prolactin (PRL), and/or its receptor are also expressed in many breast cancers, and accumulating epidemiol...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4007359/ https://ncbi.nlm.nih.gov/pubmed/23873024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.278 |
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