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Probing the instabilities in the dynamics of helical fragments from mouse PrP(C)
The first step in the formation of the protease resistant form (PrP(Sc)) of prion proteins involves a conformational transition of the monomeric cellular form of PrP(C) to a more stable aggregation prone state PrP(C*). A search of PDBselect and Escherichia coli and yeast genomes shows that the exact...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC524442/ https://ncbi.nlm.nih.gov/pubmed/15494440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404235101 |
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