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PrP(C) Homodimerization Stimulates the Production of PrP(C) Cleaved Fragments PrPN1 and PrPC1
An endoproteolytic cleavage termed α-cleavage between residues 111/112 is a characteristic feature of the cellular prion protein (PrP(C)). This cleavage generates a soluble N-terminal fragment (PrPN1) and a glycosylphosphatidylinositol-anchored C-terminal fragment (PrPC1). Independent studies demons...
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| Publicado no: | J Neurosci |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6621480/ https://ncbi.nlm.nih.gov/pubmed/22993441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2236-12.2012 |
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