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Regulation of PrP(C) signaling and processing by dimerization

The cellular prion protein (PrP(C)) is a glycosylphosphatidylinositol (GPI)-anchored protein present at the cell surface. PrP(C) N-terminal moiety is intrinsically disordered and is able to interact with a variety of ligands. Physiological ligands have neurotrophic activity, whilst others, including...

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Sonraí Bibleagrafaíochta
Príomhúdar: Roucou, Xavier
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207009/
https://ncbi.nlm.nih.gov/pubmed/25364762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2014.00057
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