Crotalus atrox venom preconditioning increases plasma fibrinogen and reduces perioperative hemorrhage in a rat model of surgical brain injury

Perioperative bleeding is a potentially devastating complication in neurosurgical patients, and plasma fibrinogen concentration has been identified as a potential modifiable risk factor for perioperative bleeding. The aim of this study was to evaluate preconditioning with Crotalus atrox venom (Cv-PC...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kim, Cherine H., McBride, Devin W., Raval, Ronak, Sherchan, Prativa, Hay, Karen L., Gren, Eric C. K., Kelln, Wayne, Lekic, Tim, Hayes, William K., Bull, Brian S., Applegate, Richard, Tang, Jiping, Zhang, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5244360/
https://ncbi.nlm.nih.gov/pubmed/28102287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40821
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