Naja sputatrix Venom Preconditioning Attenuates Neuroinflammation in a Rat Model of Surgical Brain Injury via PLA2/5-LOX/LTB4 Cascade Activation

Inflammatory preconditioning is a mechanism in which exposure to small doses of inflammatory stimuli prepares the body against future massive insult by activating endogenous protective responses. Phospholipase A2/5-lipoxygenase/leukotriene-B4 (PLA2/5-LOX/LTB4) axis is an important inflammatory signa...

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Vydáno v:Sci Rep
Hlavní autoři: Wang, Yuechun, Sherchan, Prativa, Huang, Lei, Akyol, Onat, McBride, Devin W., Zhang, John H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511148/
https://ncbi.nlm.nih.gov/pubmed/28710425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05770-7
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