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Crotalus atrox Disintegrin Reduces Hemorrhagic Transformation by Attenuating Matrix Metalloproteinase-9 Activity after Middle Cerebral Artery Occlusion in Hyperglycemic Male Rats

Hemorrhagic transformation after ischemic stroke is an independent predictor for poor outcome and is characterized by blood vessel rupture leading to brain edema. To date, no therapies for preventing hemorrhagic transformation exist. Disintegrins from the venom of Crotalus atrox have targets within...

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Detalhes bibliográficos
Publicado no:J Neurosci Res
Main Authors: McBride, Devin W., Gren, Eric C.K., Kelln, Wayne, Hayes, William K., Zhang, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6430696/
https://ncbi.nlm.nih.gov/pubmed/30242872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.24334
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