Crotalus atrox venom preconditioning increases plasma fibrinogen and reduces perioperative hemorrhage in a rat model of surgical brain injury

Perioperative bleeding is a potentially devastating complication in neurosurgical patients, and plasma fibrinogen concentration has been identified as a potential modifiable risk factor for perioperative bleeding. The aim of this study was to evaluate preconditioning with Crotalus atrox venom (Cv-PC...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Kim, Cherine H., McBride, Devin W., Raval, Ronak, Sherchan, Prativa, Hay, Karen L., Gren, Eric C. K., Kelln, Wayne, Lekic, Tim, Hayes, William K., Bull, Brian S., Applegate, Richard, Tang, Jiping, Zhang, John H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5244360/
https://ncbi.nlm.nih.gov/pubmed/28102287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40821
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