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The contribution of epistasis to the architecture of fitness in an RNA virus

The tendency for genetic architectures to exhibit epistasis among mutations plays a central role in the modern synthesis of evolutionary biology and in theoretical descriptions of many evolutionary processes. Nevertheless, few studies unquestionably show whether, and how, mutations typically interac...

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Autores principales: Sanjuán, Rafael, Moya, Andrés, Elena, Santiago F.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC524436/
https://ncbi.nlm.nih.gov/pubmed/15492220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404125101
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