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Epistasis and the Adaptability of an RNA Virus

We have explored the patterns of fitness recovery in the vesicular stomatitis RNA virus. We show that, in our experimental setting, reversions to the wild-type genotype were rare and fitness recovery was at least partially driven by compensatory mutations. We compared compensatory adaptation for gen...

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Detalles Bibliográficos
Main Authors: Sanjuán, Rafael, Cuevas, José M., Moya, Andrés, Elena, Santiago F.
Formato: Artigo
Idioma:Inglês
Publicado: Genetics Society of America 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1451175/
https://ncbi.nlm.nih.gov/pubmed/15879507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.040741
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