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Epistasis and the Adaptability of an RNA Virus

We have explored the patterns of fitness recovery in the vesicular stomatitis RNA virus. We show that, in our experimental setting, reversions to the wild-type genotype were rare and fitness recovery was at least partially driven by compensatory mutations. We compared compensatory adaptation for gen...

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Detalhes bibliográficos
Main Authors: Sanjuán, Rafael, Cuevas, José M., Moya, Andrés, Elena, Santiago F.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1451175/
https://ncbi.nlm.nih.gov/pubmed/15879507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.040741
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