Glycosylphosphatidylinositol-Anchored Anti-HIV scFv Efficiently Protects CD4 T Cells from HIV-1 Infection and Deletion in hu-PBL Mice

Despite success in viral inhibition and CD4 T cell recovery by highly active antiretroviral treatment (HAART), HIV-1 is still not curable due to the persistence of the HIV-1 reservoir during treatment. One patient with acute myeloid leukemia who received allogeneic hematopoietic stem cell transplant...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Ye, Chaobaihui, Wang, Weiming, Cheng, Liang, Li, Guangming, Wen, Michael, Wang, Qi, Zhang, Qing, Li, Dan, Zhou, Paul, Su, Lishan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5244347/
https://ncbi.nlm.nih.gov/pubmed/27881659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01389-16
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