Generation of α-1,3-galactosyltransferase knocked-out transgenic cloned pigs with knocked-in five human genes

Recent progress in genetic manipulation of pigs designated for xenotransplantation ha6s shown considerable promise on xenograft survival in primates. However, genetic modification of multiple genes in donor pigs by knock-out and knock-in technologies, aiming to enhance immunological tolerance agains...

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Bibliografiska uppgifter
I publikationen:Transgenic Res
Huvudupphovsmän: Kwon, Dae-Jin, Kim, Dong-Hwan, Hwang, In-Sul, Kim, Dong-Ern, Kim, Hyung-Joo, Kim, Jang-Seong, Lee, Kichoon, Im, Gi-Sun, Lee, Jeong-Woong, Hwang, Seongsoo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer International Publishing 2016
Ämnen:
Brief Communication
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5243873/
https://ncbi.nlm.nih.gov/pubmed/27554374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11248-016-9979-8
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