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Generation of α-1,3-galactosyltransferase knocked-out transgenic cloned pigs with knocked-in five human genes

Recent progress in genetic manipulation of pigs designated for xenotransplantation ha6s shown considerable promise on xenograft survival in primates. However, genetic modification of multiple genes in donor pigs by knock-out and knock-in technologies, aiming to enhance immunological tolerance agains...

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Bibliografiske detaljer
Udgivet i:Transgenic Res
Main Authors: Kwon, Dae-Jin, Kim, Dong-Hwan, Hwang, In-Sul, Kim, Dong-Ern, Kim, Hyung-Joo, Kim, Jang-Seong, Lee, Kichoon, Im, Gi-Sun, Lee, Jeong-Woong, Hwang, Seongsoo
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5243873/
https://ncbi.nlm.nih.gov/pubmed/27554374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11248-016-9979-8
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