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Phenotypic Alterations in Hippocampal NPY- and PV-Expressing Interneurons in a Presymptomatic Transgenic Mouse Model of Alzheimer’s Disease

Interneurons, key regulators of hippocampal neuronal network excitability and synchronization, are lost in advanced stages of Alzheimer’s disease (AD). Given that network changes occur at early (presymptomatic) stages, we explored whether alterations of interneurons also occur before amyloid-beta (A...

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書誌詳細
出版年:Front Aging Neurosci
主要な著者: Mahar, Ian, Albuquerque, Marilia Silva, Mondragon-Rodriguez, Siddhartha, Cavanagh, Chelsea, Davoli, Maria Antonietta, Chabot, Jean-Guy, Williams, Sylvain, Mechawar, Naguib, Quirion, Rémi, Krantic, Slavica
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5243860/
https://ncbi.nlm.nih.gov/pubmed/28154533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2016.00327
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