Evidence for the Involvement of Apoptosis-Inducing Factor–Mediated Caspase-Independent Neuronal Death in Alzheimer Disease

Accumulating evidence suggests the involvement of caspase-dependent and -independent mechanisms in neuronal cell death in Alzheimer disease (AD). The apoptosis-inducing factor (AIF) is a mitochondrial oxido-reductase originally characterized as a mediator of caspase-independent programmed cell death...

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Detalhes bibliográficos
Main Authors: Yu, Wenfeng, Mechawar, Naguib, Krantic, Slavica, Quirion, Rémi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861086/
https://ncbi.nlm.nih.gov/pubmed/20228227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090496
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