Regional and sub-regional differences in hippocampal GABAergic neuronal vulnerability in the TgCRND8 mouse model of Alzheimer's disease

Hippocampal network activity is predominantly coordinated by γ-amino-butyric acid (GABA)ergic neurons. We have previously hypothesized that the altered excitability of hippocampal neurons in Alzheimer's disease (AD), which manifests as increased in vivo susceptibility to seizures in the TgCRND8...

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Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: Albuquerque, Marilia S., Mahar, Ian, Davoli, Maria Antonietta, Chabot, Jean-Guy, Mechawar, Naguib, Quirion, Rémi, Krantic, Slavica
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371759/
https://ncbi.nlm.nih.gov/pubmed/25852545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2015.00030
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