Regional and sub-regional differences in hippocampal GABAergic neuronal vulnerability in the TgCRND8 mouse model of Alzheimer's disease

Hippocampal network activity is predominantly coordinated by γ-amino-butyric acid (GABA)ergic neurons. We have previously hypothesized that the altered excitability of hippocampal neurons in Alzheimer's disease (AD), which manifests as increased in vivo susceptibility to seizures in the TgCRND8...

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Pubblicato in:Front Aging Neurosci
Autori principali: Albuquerque, Marilia S., Mahar, Ian, Davoli, Maria Antonietta, Chabot, Jean-Guy, Mechawar, Naguib, Quirion, Rémi, Krantic, Slavica
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2015
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371759/
https://ncbi.nlm.nih.gov/pubmed/25852545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2015.00030
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