Septin 7 reduces nonmuscle myosin IIA activity in the SNAP23 complex and hinders GLUT4 storage vesicle docking and fusion

Glomerular epithelial cells, podocytes, are insulin responsive and can develop insulin resistance. Here, we demonstrate that the small GTPase septin 7 forms a complex with nonmuscle myosin heavy chain IIA (NMHC-IIA; encoded by MYH9), a component of the nonmuscle myosin IIA (NM-IIA) hexameric complex...

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Detalhes bibliográficos
Publicado no:Exp Cell Res
Main Authors: Wasik, Anita A., Dumont, Vincent, Tienari, Jukka, Nyman, Tuula A., Fogarty, Christopher L., Forsblom, Carol, Lehto, Markku, Lehtonen, Eero, Groop, Per-Henrik, Lehtonen, Sanna
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5243148/
https://ncbi.nlm.nih.gov/pubmed/28011197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2016.12.010
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