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Pathophysiologic changes in IA-2/IA-2β null mice are secondary to alterations in the secretion of hormones and neurotransmitters
IA-2 and IA-2β are transmembrane proteins of dense core vesicles (DCV). The deletion of these proteins results in a reduction in the number of DCV and the secretion of hormones and neurotransmitters. As a result this leads to a variety of pathophysiologic changes. The purpose of this review is to de...
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| Publicado no: | Acta Diabetol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5243143/ https://ncbi.nlm.nih.gov/pubmed/25861885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00592-015-0750-z |
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