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Disruption of gene expression rhythms in mice lacking secretory vesicle proteins IA-2 and IA-2β

Insulinoma-associated protein (IA)-2 and IA-2β are transmembrane proteins involved in neurotransmitter secretion. Mice with targeted disruption of both IA-2 and IA-2β (double-knockout, or DKO mice) have numerous endocrine and physiological disruptions, including disruption of circadian and diurnal r...

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Detalhes bibliográficos
Principais autores: Punia, Sohan, Rumery, Kyle K., Yu, Elizabeth A., Lambert, Christopher M., Notkins, Abner L., Weaver, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468428/
https://ncbi.nlm.nih.gov/pubmed/22785238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00513.2011
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