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Disturbances in the Secretion of Neurotransmitters in IA-2/IA-2β Null Mice: Changes in Behavior, Learning and Life Span
Islet-associated protein 2 (IA-2) and IA-2β are major autoantigens in type 1 diabetes and transmembrane proteins in dense core secretory vesicles (DCV) of neuroendocrine cells. The deletion of these genes results in a decrease in insulin secretion. The present study was initiated to test the hypothe...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2672562/ https://ncbi.nlm.nih.gov/pubmed/19361477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2009.01.022 |
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