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Mitochondrial respiratory gene expression is suppressed in many cancers

The fundamental metabolic decision of a cell, the balance between respiration and fermentation, rests in part on expression of the mitochondrial genome (mtDNA) and coordination with expression of the nuclear genome (nuDNA). Previously we described mtDNA copy number depletion across many solid tumor...

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Bibliographic Details
Published in:eLife
Main Authors: Reznik, Ed, Wang, Qingguo, La, Konnor, Schultz, Nikolaus, Sander, Chris
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5243113/
https://ncbi.nlm.nih.gov/pubmed/28099114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.21592
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