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Stochastic gene expression as a many-body problem

Gene expression has a stochastic component because of the single-molecule nature of the gene and the small number of copies of individual DNA-binding proteins in the cell. We show how the statistics of such systems can be mapped onto quantum many-body problems. The dynamics of a single gene switch r...

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Detalhes bibliográficos
Main Authors: Sasai, Masaki, Wolynes, Peter G.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC151348/
https://ncbi.nlm.nih.gov/pubmed/12606710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2627987100
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