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Extensive Decoupling of Metabolic Genes in Cancer

Tumorigenesis requires the re-organization of metabolism to support malignant proliferation. We examine how the altered metabolism of cancer cells is reflected in the rewiring of co-expression patterns among metabolic genes. Focusing on breast and clear-cell kidney tumors, we report the existence of...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Reznik, Ed, Sander, Chris
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427321/
https://ncbi.nlm.nih.gov/pubmed/25961905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004176
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