Evaluating acetate metabolism for imaging and targeting in multiple myeloma

PURPOSE: We hypothesized that in multiple myeloma cells (MMC), high membrane biosynthesis will induce acetate uptake in vitro and in vivo. Here, we studied acetate metabolism and targeting in MMC in vitro and tested the efficacy of (11)C-acetate-PET (positron emission tomography) to detect and quant...

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Bibliografiska uppgifter
I publikationen:Clin Cancer Res
Huvudupphovsmän: Fontana, Francesca, Ge, Xia, Su, Xinming, Hathi, Deep, Xiang, Jingyu, Cenci, Simone, Civitelli, Roberto, Shoghi, Kooresh I., Akers, Walter J., D’avignon, Andre, Weilbaecher, Katherine N., Shokeen, Monica
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241171/
https://ncbi.nlm.nih.gov/pubmed/27486177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2134
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