Evaluating acetate metabolism for imaging and targeting in multiple myeloma

PURPOSE: We hypothesized that in multiple myeloma cells (MMC), high membrane biosynthesis will induce acetate uptake in vitro and in vivo. Here, we studied acetate metabolism and targeting in MMC in vitro and tested the efficacy of (11)C-acetate-PET (positron emission tomography) to detect and quant...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Clin Cancer Res
Prif Awduron: Fontana, Francesca, Ge, Xia, Su, Xinming, Hathi, Deep, Xiang, Jingyu, Cenci, Simone, Civitelli, Roberto, Shoghi, Kooresh I., Akers, Walter J., D’avignon, Andre, Weilbaecher, Katherine N., Shokeen, Monica
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241171/
https://ncbi.nlm.nih.gov/pubmed/27486177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2134
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