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Evaluating acetate metabolism for imaging and targeting in multiple myeloma

PURPOSE: We hypothesized that in multiple myeloma cells (MMC), high membrane biosynthesis will induce acetate uptake in vitro and in vivo. Here, we studied acetate metabolism and targeting in MMC in vitro and tested the efficacy of (11)C-acetate-PET (positron emission tomography) to detect and quant...

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Bibliografske podrobnosti
izdano v:Clin Cancer Res
Main Authors: Fontana, Francesca, Ge, Xia, Su, Xinming, Hathi, Deep, Xiang, Jingyu, Cenci, Simone, Civitelli, Roberto, Shoghi, Kooresh I., Akers, Walter J., D’avignon, Andre, Weilbaecher, Katherine N., Shokeen, Monica
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241171/
https://ncbi.nlm.nih.gov/pubmed/27486177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2134
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