Evaluating acetate metabolism for imaging and targeting in multiple myeloma

PURPOSE: We hypothesized that in multiple myeloma cells (MMC), high membrane biosynthesis will induce acetate uptake in vitro and in vivo. Here, we studied acetate metabolism and targeting in MMC in vitro and tested the efficacy of (11)C-acetate-PET (positron emission tomography) to detect and quant...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Fontana, Francesca, Ge, Xia, Su, Xinming, Hathi, Deep, Xiang, Jingyu, Cenci, Simone, Civitelli, Roberto, Shoghi, Kooresh I., Akers, Walter J., D’avignon, Andre, Weilbaecher, Katherine N., Shokeen, Monica
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241171/
https://ncbi.nlm.nih.gov/pubmed/27486177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2134
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