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Structural basis of influenza virus fusion inhibition by the antiviral drug Arbidol

The broad-spectrum antiviral drug Arbidol shows efficacy against influenza viruses by targeting the hemagglutinin (HA) fusion machinery. However, the structural basis of the mechanism underlying fusion inhibition by Arbidol has remained obscure, thereby hindering its further development as a specifi...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kadam, Rameshwar U., Wilson, Ian A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240704/
https://ncbi.nlm.nih.gov/pubmed/28003465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1617020114
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