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Mechanism of Inhibition of Enveloped Virus Membrane Fusion by the Antiviral Drug Arbidol

The broad-spectrum antiviral arbidol (Arb) inhibits cell entry of enveloped viruses by blocking viral fusion with host cell membrane. To better understand Arb mechanism of action, we investigated its interactions with phospholipids and membrane peptides. We demonstrate that Arb associates with phosp...

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Detalhes bibliográficos
Main Authors: Teissier, Elodie, Zandomeneghi, Giorgia, Loquet, Antoine, Lavillette, Dimitri, Lavergne, Jean-Pierre, Montserret, Roland, Cosset, François-Loïc, Böckmann, Anja, Meier, Beat H., Penin, François, Pécheur, Eve-Isabelle
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026800/
https://ncbi.nlm.nih.gov/pubmed/21283579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015874
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