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Mechanism of Inhibition of Enveloped Virus Membrane Fusion by the Antiviral Drug Arbidol

The broad-spectrum antiviral arbidol (Arb) inhibits cell entry of enveloped viruses by blocking viral fusion with host cell membrane. To better understand Arb mechanism of action, we investigated its interactions with phospholipids and membrane peptides. We demonstrate that Arb associates with phosp...

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Main Authors: Teissier, Elodie, Zandomeneghi, Giorgia, Loquet, Antoine, Lavillette, Dimitri, Lavergne, Jean-Pierre, Montserret, Roland, Cosset, François-Loïc, Böckmann, Anja, Meier, Beat H., Penin, François, Pécheur, Eve-Isabelle
格式: Artigo
語言:Inglês
出版: Public Library of Science 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026800/
https://ncbi.nlm.nih.gov/pubmed/21283579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015874
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