Structural basis for suppression of a host antiviral response by influenza A virus

Influenza A viruses are responsible for seasonal epidemics and high mortality pandemics. A major function of the viral NS1A protein, a virulence factor, is the inhibition of the production of IFN-β mRNA and other antiviral mRNAs. The NS1A protein of the human influenza A/Udorn/72 (Ud) virus inhibits...

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Autors principals: Das, Kalyan, Ma, Li-Chung, Xiao, Rong, Radvansky, Brian, Aramini, James, Zhao, Li, Marklund, Jesper, Kuo, Rei-Lin, Twu, Karen Y., Arnold, Eddy, Krug, Robert M., Montelione, Gaetano T.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2522260/
https://ncbi.nlm.nih.gov/pubmed/18725644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805213105
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