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Characterization of a P-Rex1 gene signature in breast cancer cells
The Rac nucleotide Exchange Factor (Rac-GEF) P-Rex1 is highly expressed in breast cancer, specifically in the luminal subtype, and is an essential mediator of actin cytoskeleton reorganization and cell migratory responses induced by stimulation of ErbB and other tyrosine-kinase receptors. Heregulin...
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| Veröffentlicht in: | Oncotarget |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Impact Journals LLC
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5239479/ https://ncbi.nlm.nih.gov/pubmed/27351228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10285 |
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