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P-REX1-Independent, Calcium-Dependent RAC1 Hyperactivation in Prostate Cancer

The GTPase Rac1 is a well-established master regulator of cell motility and invasiveness contributing to cancer metastasis. Dysregulation of the Rac1 signaling pathway, resulting in elevated motile and invasive potential, has been reported in multiple cancers. However, there are limited studies on t...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Baker, Martin J., Abba, Martín C., Garcia-Mata, Rafael, Kazanietz, Marcelo G.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072377/
https://ncbi.nlm.nih.gov/pubmed/32092966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12020480
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