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Characterization of a P-Rex1 gene signature in breast cancer cells

The Rac nucleotide Exchange Factor (Rac-GEF) P-Rex1 is highly expressed in breast cancer, specifically in the luminal subtype, and is an essential mediator of actin cytoskeleton reorganization and cell migratory responses induced by stimulation of ErbB and other tyrosine-kinase receptors. Heregulin...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Barrio-Real, Laura, Wertheimer, Eva, Garg, Rachana, Abba, Martin C., Kazanietz, Marcelo G.
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5239479/
https://ncbi.nlm.nih.gov/pubmed/27351228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10285
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