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Characterization of a P-Rex1 gene signature in breast cancer cells

The Rac nucleotide Exchange Factor (Rac-GEF) P-Rex1 is highly expressed in breast cancer, specifically in the luminal subtype, and is an essential mediator of actin cytoskeleton reorganization and cell migratory responses induced by stimulation of ErbB and other tyrosine-kinase receptors. Heregulin...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Barrio-Real, Laura, Wertheimer, Eva, Garg, Rachana, Abba, Martin C., Kazanietz, Marcelo G.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5239479/
https://ncbi.nlm.nih.gov/pubmed/27351228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10285
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