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Binding of N-methylscopolamine to the extracellular domain of muscarinic acetylcholine receptors
Interaction of orthosteric ligands with extracellular domain was described at several aminergic G protein-coupled receptors, including muscarinic acetylcholine receptors. The orthosteric antagonists quinuclidinyl benzilate (QNB) and N-methylscopolamine (NMS) bind to the binding pocket of the muscari...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5238504/ https://ncbi.nlm.nih.gov/pubmed/28091608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40381 |
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